Dan Makham Tia (, ) is a district (amphoe) in the southern part of Kanchanaburi province, western Thailand.
The area of Dan Makham Tia was settled more than 200 years. It was a border village of Mueang Kanchanaburi adjacent to Burma.
The area had a short Makham tree (Tamarindus indica), so people called the village Ban Nong Makham Tia. Later was changed to be Dan Makham Tia.
The minor district (king amphoe) was created on 1 April 1990 by splitting off the three tambons Dan Makham Tia, Klondo, and Chorakhe Phueak from Mueang Kanchanaburi district. It was upgraded to a full district on 8 September 1995.
Neighboring districts are (from the north clockwise) Mueang Kanchanaburi, Tha Muang of Kanchanaburi Province, Chom Bueng and Suan Phueng of Ratchaburi province.
The most important water resources in the area are the Khwae Noi and Phachi River.
The district is divided into four subdistricts (tambons), which are further subdivided into 41 administrative villages (mubans).
As of December 2024 there is one municipal (thesaban) area in the district: Dan Makham Tia subdistrict municipality (thesaban tambon) covers parts of the same-named subdistrict.
The non-municipal areas are administered by four subdistrict administrative organizations - SAO (ongkan borihan suan tambon - o bo toh).
Dan Makham Tia district is served by one hospital
In the district there are six health-promoting hospitals in total.
There are thirty-two Theravada Buddhist temples in the district.