2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine (DOEF) is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists DOEF's dose as 2 to 3.5mg orally and its duration as 12 to 16hours. The drug's onset was 1 to 2hours and peak effects occurred after 3hours. The effects of DOEF were reported to include unworldliness, closed-eye imagery no appreciable open-eye visuals or not highly visual, time dilation, music and erotic enhancement, no body discomfort, insomnia, and sleep disruption, among others.
The chemical synthesis of DOEF has been described.
Analogues of DOEF include 2C-EF, DOET, DOTFE, DOPF, and DOTFM, among others.
DOEF was first described in the scientific literature by Alexander Shulgin and colleagues in 1988. Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.
DOEF is a controlled substance in Canada under phenethylamine blanket-ban language.