The D<sub>1</sub>-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine. The D<sub>1</sub>-like subfamily consists of two G proteinâÂÂcoupled receptors that are coupled to G<sub>s</sub> and mediate excitatory neurotransmission, of which include D<sub>1</sub> and D<sub>5</sub>. For more information, please see the respective main articles of the individual subtypes.