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Delta1-piperideine-2-carboxylate reductase

In enzymology, Delta1-piperideine-2-carboxylate reductase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are (–)-pipecolic acid and oxidised nicotinamide adenine dinucleotide phosphate (NADP<sup>+</sup>). Its products are 1-piperideine-2-carboxylic acid, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.

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