D-xylose 1-dehydrogenase

In enzymology, D-xylose 1-dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are D-xylose, shown in its open-chain aldehydo form, and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its 3 products are D-xylono-1,5-lactone, reduced NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-xylose:NAD⁺ 1-oxidoreductase. Other names in common use include NAD⁺-D-xylose dehydrogenase, D-xylose dehydrogenase, and (NAD⁺)-linked D-xylose dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.

See also

• D-xylose 1-dehydrogenase (NADP+) which catalyses the same reaction using the cofactor nicotinamide adenine dinucleotide phosphate

References