<small>D</small>-threonine aldolase (, <small>D</small>-TA, DTA, low specificity <small>D</small>-TA, low specificity <small>D</small>-threonine aldolase) is an enzyme with systematic name <small>D</small>-threonine acetaldehyde-lyase (glycine-forming). This enzyme catalyses the following chemical reaction
This pyridoxal-phosphate protein is activated by divalent metal cations (e.g. Co<sup>2+</sup>, Ni<sup>2+</sup>, Mn<sup>2+</sup> or Mg<sup>2+</sup>).