The enzyme <small>D</small>-fuconate dehydratase () catalyzes the chemical reaction.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is <small>D</small>-fuconate hydro-lyase (2-dehydro-3-deoxy-<small>D</small>-fuconate-forming). This enzyme is also called <small>D</small>-fuconate hydro-lyase. This enzyme participates in fructose and mannose metabolism.