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D-alanine—D-serine ligase

<small>D</small>-Alanine—<small>D</small>-serine ligase (, VanC, VanE, VanG) is an enzyme with systematic name D-alanine:D-serine ligase (ADP-forming). This enzyme catalyses the following chemical reaction

<small>D</small>-alanine + <small>D</small>-serine + ATP <small>D</small>-alanyl-<small>D</small>-serine + ADP + phosphate

The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.

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