Cyclopentadecanolide is an organic compound with the formula . A colorless solid, it is classified as macrolide lactone. It has some use in perfumery.
Cyclopentadecanolide occurs in small quantities in angelica root essential oil and is responsible for its musklike odor.
Cyclopentadecanolide is produced by ring expansion of cyclotetradecanone. Another synthesis route is the depolymerization of polyesters of 15-hydroxypentadecanoic acid.
Cyclopentadecanolide is used as a musklike perfume fixative in fine fragrances and as a flavoring agent. Its aroma is described as "musk, animal, powdery, natural, fruity, tobacco, coumarinic, heliotrope, and licorice". It is a substitute for the extremely expensive animal musk.