Crispen Mutakanyi (born 15 March 1970) is a retired male middle-distance runner from Zimbabwe. He represented his country at the 2000 Summer Olympics in Sydney, Australia and the 1999 World Championships in Seville, Spain.
Mutakanyi has personal bests in the 800 metres of 1:45.1 minutes outdoors (Harare 1998) and 1:52.94 minutes indoors (Lisbon 2001).