Conus isabelarum is a species of sea snail, a marine gastropod mollusk in the family Conidae, the cone snails and their allies.
Like all species within the genus Conus, these snails are predatory and venomous. They are capable of stinging humans.
The size of the shell varies between 17 mm and 30 mm. The color of the shell is tan or brown with white splashes.
This species occurs in the Atlantic Ocean off the island of Maio, Cape Verde.