NA-169 Rahim Yar Khan-I () is a constituency for the National Assembly of Pakistan.
General elections were held on 10 October 2002. Makhdoom Syed Ahmad Alam Anwar an Independent candidate won by 74,933 votes.
General elections were held on 18 February 2008. Hamid Saeed Kazmi of PPP won by 65,395 votes.
General elections were held on 11 May 2013. Khwaja Ghulam Rasool Koreja of PPP won by 80,499 votes and became the member of National Assembly.
General elections were held on 25 July 2018.
General elections were held on 8 February 2024. Makhdoom Syed Murtaza Mehmood won the election with 81,187 votes.