The national federations of the UCI form confederations by continent. In the Americas, this body is the Confederación Panamericana de Ciclismo (the Pan American Cycling Confederation), also shortened to COPACI. COPACI was founded in 1922 in Montevideo, Uruguay, and is presently headquartered in Havana, Cuba.
COPACI serves as the sponsor of the annual Pan American Road and Track Championships and a key organisation for the UCI America Tour.
As of June 2021, COPACI consists of 44 full member federations and 5 associate member federations. In 2025, the Mexican Cycling Federation was excluded and replaced by the Unión Ciclista de México.
Following the dissolution of the Netherlands Antilles in 2010, its cycling federation was also disbanded and replaced with those of the three Caribbean member countries of the Kingdom of the Netherlands (Aruba, Curaçao, and Sint Maarten).