Comstock is a surname of English origin. Notable people with the surname include:
- A. B. Comstock (1857âÂÂ1937), American politician
- Ada Comstock (1876âÂÂ1973), U.S. women's education pioneer
- Adam Comstock (1740âÂÂ1819), Revolutionary War veteran and New York politician
- Albert C. Comstock (1845âÂÂ1910), New York lawyer and politician
- Anna Botsford Comstock (1854âÂÂ1930), U.S. artist, educator, and conservationist
- Anthony Comstock (1844âÂÂ1915), U.S. moral reformer and namesake of the Comstock laws
- Barbara Comstock (born 1959), member of the U.S. House of Representatives
- Bobby Comstock (1941âÂÂ2020), American rock and roll singer
- Charles Carter Comstock (1818âÂÂ1900), U.S. politician from Michigan
- Christopher Comstock (1635âÂÂ1702), early settler of Norwalk, Connecticut and a deputy of the General Assembly of the Colony of Connecticut
- Christopher Comstock (born 1992), birth name of Marshmello, American electronic dance music producer and DJ
- Cicero Comstock (1817âÂÂ1871), Wisconsin state senator, Milwaukee comptroller
- Cyrus B. Comstock (1831âÂÂ1910), U.S. Army corps of engineers officer, member of the NAS
- Rev. Cyrus Comstock (1765âÂÂ1853), New York State preacher and inventor of the horse-drawn buckboard wagon.
- Daniel Frost Comstock (1883âÂÂ1970), U.S. physicist and engineer
- Daniel Webster Comstock (1840âÂÂ1917), U.S. politician from Indiana
- Dorothy Comstock Riley (1924âÂÂ2004), lawyer and judge from the U.S. state of Michigan
- Frank Comstock (1922âÂÂ2013), American music arranger, composer and conductor
- Frank Comstock (politician) (1856âÂÂ1914), American politician
- George F. Comstock (1811âÂÂ1892), Chief Judge of the New York Court of Appeals 1860âÂÂ1861
- George G. Comstock (1855âÂÂ1934), American astronomer
- Helen Field Comstock (1840âÂÂ1930), American poet, philanthropist
- Henry Tompkins (or Thomas) Paige Comstock (1820âÂÂ1870), American miner after whom Comstock Lode was named
- Harriet Theresa Comstock (1860âÂÂ1925), American novelist and author of children's books
- Isaac N. Comstock (1808âÂÂ1883), New York politician and prison warden
- John Henry Comstock (1849âÂÂ1931), U.S. entomologist, co-creator of the Comstock-Needham system
- Keith Comstock (born 1955), major league baseball player
- Nanette Comstock (1866âÂÂ1942), Broadway actress
- Noah D. Comstock (1832âÂÂ1890), American politician
- Oliver C. Comstock (1780âÂÂ1860), U.S. politician from New York
- Samuel Comstock (1680âÂÂ1752), member of the Connecticut House of Representatives from Norwalk, Connecticut
- Solomon Gilman Comstock (1842âÂÂ1933), U.S. politician from Minnesota
- William Comstock (1877âÂÂ1949), Governor of Michigan
- William Henry Comstock (1830âÂÂ1919), American-Canadian businessman and politician
Fictional characters:
- Earl Comstock, character in Neal Stephenson's novel Cryptonomicon
- Gordon Comstock, character in George Orwell's novel Keep the Aspidistra Flying
- Julian Comstock, character in Robert Charles Wilson's novel '
- Radborne Comstock, character in Elizabeth Hand's novel Mortal Love
- Roger Comstock, character in Neal Stephenson's The Baroque Cycle of novels
- Zachary Hale Comstock, main antagonist in the video game BioShock Infinite
- Magenta Comstock: historical figure within the universe of the Harry Potter franchise