Isale is a commune of Bujumbura Rural Province in Burundi. It is also the capital of Bujumbura Rural Province.
It contains the collines of Benga, Karunga, Bibare, Kwigere, Rutegama, Rushubi, Cirisha, Nyambuye, Nyarumpongo, Caranka, Nyakibande, Nyarukere, Buyimba, Sagara and Kibuye.