Commerce Bank Building is a tall neoclassical style office building located on 416 Main Street in Downtown Peoria. The building has 17 floors and was built in 1920. Upon its completion it became the tallest building in Peoria, surpassing the tall Cathedral of St. Mary of the Immaculate Conception which was built in 1889. The building would later lose the title to the Peoria Twin Towers in 1984. The building was designed by Hewitt & Emerson.
The Peoria Life Insurance Company bought the land for the building in 1917, which was the former site of Rouse's Opera Hall. The Peoria Life Insurance Company would commission local architectural firm Hewitt & Emerson to design the building. Construction began in the Spring of 1918, but was halted for around four months due to WW1, construction resumed after the end of the war and the building was finally completed in 1920.
The top of the building is adorned by a lantern, which if included in the buildings height would make it tall.
The building would undergo renovations in 2022.
The building and most of Downtown Peoria was listed on the National Register of Historic Places in December 2018.