Colette Irwin-Knott is an American academic administrator. She served as the interim president of Valparaiso University from September 1, 2020, to February 28, 2021. Irwin-Knott has served on the Valparaiso University Board of Directors since 2009.
Irwin-Knott graduated from Valparaiso University in 1981 with a bachelor of science degree. She worked in public finance in Indianapolis, Indiana, until her retirement in 2014.