Coles Branch is a long tributary to Crabtree Creek in Wake County, North Carolina, and is classed as a 2nd order stream on the EPA waters site.
Coles Branch rises in a pond in western Cary, North Carolina, and then flows northwest to Crabtree Creek. It is a developed watershed with seven percent of the watershed considered to be forested.
Coles Branch drains of area in the western part of Cary. Coles Branch is underlaid by the Deep River Basin. The watershed receives an average of per year of precipitation and has a wetness index of 413.95.