Clear Creek is a stream in eastern Daviess County in the U.S. state of Missouri. It is a tributary of the Grand River.
The stream headwaters arise at approximately 1.5 miles east of Jamesport. The stream flows to the south meandering briefly into Livingston County in two places before turning to the south-southwest and crossing under Missouri Route 190 before reaching its confluence with the Grand River approximately 1.5 miles west of Lock Springs at .
Clear Creek most likely was named for the clarity of water.