Cladispa quadrimaculata is a species of beetle of the family Chrysomelidae. It is found in French Guiana and Guyana.
Adults reach a length of about 7.11 mm. The head, pronotum and scutellum are yellow. The elytra are also yellow, but each with two large brown spots.
The recorded host plant for this species is Cyrtopodium andersonii.