Cicloprolol (; developmental code name SL-75177), or cycloprolol (), is a ò-adrenergic receptor antagonist (beta blocker) described as an antihypertensive agent which was never marketed. It has weak partial agonist or intrinsic sympathomimetic activity (30%) at the ò-adrenergic receptors. This is higher than that of many other beta blockers but is lower than that of xamoterol (45%). The drug is selective for the ò<sub>1</sub>-adrenergic receptor. It has been studied in the treatment of heart failure.
The chemical structure of cicloprolol is very similar to that of betaxolol.
Cicloprolol can be synthesized starting from 4-benzyloxyphenol.