Childress Independent School District is a public school district based in Childress, Texas, United States. Located in Childress County, small portions of the district extend into Cottle, Hall, and Hardeman Counties. The current learning system for Childress is CSCOPE. Childress also participates in University Interscholastic League activities.
In 2009, the school district was rated "recognized" by the Texas Education Agency.
On July 1, 1985, the Estelline Independent School District merged into Childress ISD.