Charles James may refer to:
- Charles James (British Army officer) (1757/8âÂÂ1821), English army officer and writer
- Charles James (attorney) (born 1954), former U.S. assistant attorney general
- Charles James (American football) (born 1990), American football cornerback
- Charlie James (baseball) (born 1937), baseball player
- Charles James (chemist) (1880âÂÂ1928), discoverer of lutetium
- Charles James (designer) (1906âÂÂ1978), fashion designer
- Charlie James (footballer) (1874âÂÂ1948), Australian rules footballer
- Charles James (footballer) (1882âÂÂ1960), footballer for Stoke
- Charles James (MP) (1817âÂÂ1890), British politician
- Charles James (rugby league) (1891âÂÂ1917), New Zealand rugby league footballer
- Charles C. James (1882âÂÂ1957), American consulting accountant
- Charlie Hamilton James (born c. 1974), English photographer, television cameraman and presenter
- Charles Holloway James (1893âÂÂ1953), architect
- Charles O. James, Texas state senator, 1899âÂÂ1903; state representative, 1893âÂÂ1895, see Texas Senate, District 2
- Charles Pinckney James (1818âÂÂ1899), U.S. federal judge
- Charles Tillinghast James (1805âÂÂ1862), U.S. Senator from Rhode Island
- Chuck James (born 1981), baseball player
- Charles James (cricketer) (1885âÂÂ1950), English cricketer
- Captain Charles James, fictional character from Our Girl