Challwa Mayu (Quechua 'fish', 'river', "fish river", hispaniciced spelling Challhua Mayu) is a Bolivian village in the south-east of the Cochabamba Department located in the Arani Province, Vacas Municipality, north-west of Vacas. At the time of census 2001 it had 770 inhabitants.
The Ismael Montes Teacher Training College is situated in Challwa Mayu.