Chagres District () is a district (distrito) of Colón Province in Panama. The population according to the 2000 census was 9,191; the latest official estimate (for 2019) is 11,342. The district covers a total area of 445 km<sup>2</sup>. The capital lies at the town of Nuevo Chagres.
Chagres District is divided administratively into the following corregimientos: