The Cesar River () is a river in northern Colombia which is a part of the Magdalena Basin. It flows through the Cesar-RancherÃÂa Basin and separates the Sierra Nevada de Santa Marta from the mountain ranges of the SerranÃÂa del Perijá, an extension of the Cordillera Oriental. It flows north to south, down from the Sierra Nevada de Santa Marta in the Guajira Department onto the Cesar Department and flowing into the Zapatosa Marsh where it turns to the southwest and discharges into the Magdalena River after 280 kilometers. Valledupar is the only major city on its route.