The Central Mass. Athletic Conference (CMAC) is the newest High School sports league in the Massachusetts Interscholastic Athletic Association. The conference is the result of the Inter-High League, Southern Worcester County League, Dual Valley Conference, Colonial Athletic League, and Central Mass. Conference combining to create a super conference. The conference includes 34 Public, Vocational, Charter, and Private schools from the Worcester County and Middlesex County. The newly created conference is a member of the 2nd district of the Massachusetts Interscholastic Athletic Association's nine districts, being the only athletic league assigned to the district.
The conference was created for schools to do better under the new MIAA state tournament format; allowing them to more easily schedule stronger opponents. This is done by creating alignments based on power rankings from recent seasons at the beginning of each year.
<nowiki>*</nowiki>Main South is the combination of Claremont Academy and University Park Campus School, both from the Inter-High league
â St. Paul Diocesan was originally founded as Holy Name High school in 1942. In 2020 it merged with Saint Peter-Marian High School to become St. Paul Diocesan
Below is a list of state championships for sports sanctioned by the Massachusetts Interscholastic Athletic Association won by schools while they were members of the Central Massachusetts Athletic Conference since the league's inception in the fall of 2025.