The Central District of Shushtar County () is in Khuzestan province, Iran. Its capital is the city of Shushtar.
After the 2006 National Census, the village of Shahrak-e Shahid Sharafat rose to city status as Sharafat. After the 2011 census, Miyan Ab and Miyan Ab-e Shomali Rural Districts were separated from the district in the formation of Miyan Ab District, and the village of Sardarabad was elevated to city status as Sardaran.
At the time of the 2006 census, the Central District's population was 161,714 in 33,999 households. The following census in 2011 counted 169,224 people in 40,566 households. The 2016 census measured the population of the district as 139,040 inhabitants in 37,243 households.