The Central District of Qaen County () is in South Khorasan province, Iran. Its capital is the city of Qaen.
At the time of the 2006 National Census, the district's population was 62,040 in 16,239 households. The following census in 2011 counted 70,686 people in 19,432 households. The 2016 census measured the population of the district as 73,917 inhabitants in 21,798 households.