The Central District of Meshgin Shahr County () is in Ardabil province, Iran. Its capital is the city of Meshginshahr.
In 2012, Meshgin-e Gharbi and Shaban Rural Districts were separated from the district in the formation of Qosabeh District. At the same time, the village of Qosabeh was converted to a city. The village of Alni also rose to city status in 2019.
At the time of the 2006 National Census, the district's population was 112,128 in 26,284 households. The following census in 2011 counted 114,726 people in 30,979 households. The 2016 census measured the population of the district as 107,557 inhabitants living in 32,434 households.