The Central District of Khorramshahr County () is in Khuzestan province, Iran. Its capital is the city of Khorramshahr.
After the 2016 National Census, Kut-e Sheykh neighborhood of the city of Khorramshahr was elevated to city status as Moqavemat.
At the time of the 2006 National Census, the district's population was 147,642 in 31,001 households. The following census in 2011 counted 155,434 people in 40,048 households. The 2016 census measured the population of the district as 161,820 inhabitants in 44,829 households.