The Central District of Khorramabad County () is in Lorestan province, Iran. Its capital is the city of Khorramabad.
At the time of the 2006 National Census, the district's population was 417,556 in 94,201 households. The following census in 2011 counted 445,627 people in 118,398 households. The 2016 census measured the population of the district as 463,599 inhabitants in 133,110 households.