The Central District of Khaf County () is in Razavi Khorasan province, Iran. Its capital is the city of Khaf.
At the time of the 2006 National Census, the district's population was 40,652 in 9,114 households. The following census in 2011 counted 46,273 people in 11,459 households. The 2016 census measured the population of the district as 52,899 inhabitants in 14,062 households.