Cedar Creek is a stream in Clark County in the U.S. state of Missouri. It is a tributary of the Des Moines River.
The stream headwaters arise northwest of the community of Anson at . It flows east crossing under Missouri Route 81 north of Anson. It continues to the southeast and east approximately four miles to its confluence with the Des Moines River at approximately two miles south of Croton, Iowa.
Cedar Creek was named for the red cedar timber along its course.