Cauvery South Wildlife Sanctuary is a protected area located in Dharmapuri and Krishnagiri of the Indian state of Tamil Nadu. The sanctuary covers an area of and was notified in 2022.
The sanctuary connects the Cauvery North Wildlife Sanctuary of Tamil Nadu with the Cauvery Wildlife Sanctuary in Karnataka and forms a large, contiguous network of protected areas for wildlife. The Nandimangalam-Ulibanda Corridor and the Kovaipallam-Anebiddahalla Corridor which are one of the largest elephant corridors also fall in this area.
The sanctuary is home to 35 species of mammals and 238 species of birds. Major fauna includes Leith's soft shelled turtles, Smooth coated otters, marsh crocodile, Grizzled giant squirrel, Four-horned antelope, and Lesser Fish Eagle.