Caumont-sur-Durance (, literally Caumont on Durance; ) is a commune in the Vaucluse department in the Provence-Alpes-Côte d'Azur region of Southeastern France.
The river Calavon flows into the Durance in the commune. It is home to the Charterhouse of Bonpas (French: Chartreuse de Bonpas), a former Carthusian priory and historic monument.