Cathedral of Saint Nicholas () is a Ukrainian Orthodox church located in the Tsentralnyi District, Mariupol, Ukraine.
The cathedral is a six-domed church, built between 1989 and 1991 and designed by the architects AD Kljujew & NJ Erenburg (Russian: ÃÂ. ÃÂ. ÃÂûÃÂÃÂò & ÃÂ. î. ÃÂÃÂõýñÃÂÃÂó). The artist Sergej Alekseevich Barannik decorated the church.
In 2022, during the Siege of Mariupol, the cathedral was heavily damaged.