Cathedral High School is an American all-girls', private Catholic high school in the borough of Manhattan in New York City, New York It is located within the Archdiocese of New York.
The school was established in 1905 by the Sisters of Charity. In 1973, the high school moved to East 56th Street into the newly built Terence Cardinal Cooke Building that served as administrative offices the Archdiocese of New York and also housed the Church of St. John the Evangelist.
In 2023, it moved from 56th Street into a four-story building on East 97th Street owned by the St. Francis de Sales Parish that was previously occupied by the Marymount School of New York.
In September 2025, the school's board of trustees announced that it would close permanently after the 2025âÂÂ2026 school year, citing high operating costs and declining enrollment.
Enrollment is open to young women of all cultures and faiths.
There are plenty of college preparatory courses as well as Advanced Placement classes, including biology, calculus, English, history, literature, physics, and Spanish.
A course on religion is mandatory on an annual basis; however, the school welcomes students of all faiths.