Castione Andevenno is a comune (municipality) in the Province of Sondrio in the Italian region Lombardy, located about northeast of Milan and about west of Sondrio. As of 31 December 2004, it had a population of 1,545 and an area of .
Castione Andevenno borders the following municipalities: Albosaggia, Caiolo, Postalesio, Sondrio, Torre di Santa Maria.
The 18th-century church of San Martino is found in the territory.