Cassandra Kulukundis (born 1971) is an American casting director. For her work on the film One Battle After Another (2025), she became the first recipient of the Academy Award for Best Casting.
Kulukundis was born in 1971. She was born in the United States and is of Greek descent. She is the daughter of Manuel Michael Kulukundis, and the granddaughter of Manuel E. Kulukundis, both of the Kulukundis shipping family. Her first cousin once removed is entrepreneur and theater impresario Eddie Kulukundis.
She graduated from Vassar College in 1993. She began her career as an intern on director Paul Thomas Anderson's debut film Hard Eight (1996). She won the inaugural Best Casting Academy Award for the film One Battle After Another (2025).
As of 2026, Kulukundis lives in Sutton House in New York City.