Casaletto Lodigiano (Lodigiano: ) is a comune (municipality) in the Province of Lodi in the Italian region Lombardy, located about southeast of Milan and about west of Lodi.
Casaletto Lodigiano borders the following municipalities: Cerro al Lambro, San Zenone al Lambro, Bascapè, Salerano sul Lambro, Caselle Lurani.