El Moro Canyon virus is a single-stranded, negative sense RNA virus of the genus Orthohantavirus. It is a causative agent of Hantavirus pulmonary syndrome.
El Moro Canyon virus was isolated from western harvest mice (Reithrodontomys megalotis), in El Moro Canyon in southeastern Colorado in 1995.
Carrizal virus and Huitzilac virus, two additional strains, were first identified in Mexican wild rodents located in Morelos and Guerrero, Mexico.