The canton of Calais-Centre is a former canton situated in the department of the Pas-de-Calais and in the Nord-Pas-de-Calais region of northern France. It was disbanded following the French canton reorganisation which came into effect in March 2015. It consisted of 3 communes, which joined the canton of Calais-2 in 2015. It had a total of 27,832 inhabitants (2012).
The canton is organised around Calais in the arrondissement of Calais. The altitude varies from (Les Attaques) to (Calais) for an average altitude of .
The canton comprised 3 communes: