Cantagalo is a district of São Tomé and PrÃÂncipe, on São Tomé Island. Its area is , and its population is 17,161 (2012). The district seat is Santana. Cantagalo is divided into the two statistical subdistricts Santana and Ribeira Afonso.
The main settlement is the town Santana. Other settlements are:
Cantagalo currently has seven seats in the National Assembly.