Callohesma quadrimaculata is a species of bee in the family Colletidae and the subfamily Euryglossinae. It is endemic to Australia. It was described in 1879 by English entomologist Frederick Smith.
The species occurs in south-east Queensland. The type locality is Helidon, in the Lockyer Valley.
The adults are flying mellivores. Flowering plants visited by the bees include Angophora species.