Calligrapha heterothecae is a species of leaf beetle belonging to the family Chrysomelidae, in the subgenus Zygogramma, which was formerly a genus.
C. heterothecae is a small leaf beetle with a brown pronotum and yellow elytra marked with elongated brown stripes.
C. heterothecae is native to North America. Adult beetles are associated exclusively with camphorweed (Heterotheca subaxillaris).
C. heterothecae is predated by the two-spotted stink bug (Perillus bioculatus) and the spined soldier bug (Podisus maculiventris).