The third season began with a small pre-season on February 1, 2010 and consisted on competing teams for money. At the end of this pre-season all the money raised so far was donated to the victims of the earthquake of February 27 that affected Chile.
The new season of Calle 7 started on March 15, 2010, with new players and game mode in couples. Like a previous seasons the nominees were chosen every day according to the team that lost, in this case the couple. The couple with less score of elimination on Friday and was eliminated by a sealed envelope from the beginning of the program knew whether it was male or female.
The grand finale was on June 5 and the winners were the winner of Pelotón Francisco "Pancho" RodrÃÂguez and Maite Orsini, winning 6 million Chilean pesos, the second place was Federico Koch and Camila Nash winning 1 million Chilean pesos. The "Spirit of Calle 7" award was won by Alain Soulat.