Calco (Brianzöö: ) is a comune (municipality) in the Province of Lecco in the Italian region Lombardy, located about northeast of Milan and about south of Lecco. As of 31 December 2004, it had a population of 4,284 and an area of .
Calco borders the following municipalities: Brivio, Imbersago, Merate, Olgiate Molgora, Pontida, Villa d'Adda. It is served by Olgiate-Calco-Brivio railway station.