Cai Changgui (, born 15 April 1983) is a Chinese goalball player. He won a gold medal at the 2008 Summer Paralympics.
He competed in the 2012 Summer Paralympics despite an infection and the doctor's bed-rest order, after sneaking out of the hospital.
Cai lost his eyesight when he was 10 years old, due to a medical accident involving an injection.
Cai is married to goalball player Wang Shasha, who is also blind. The couple live in Hangzhou. He has a black Labrador guide dog named "Sanhao" ().