CFU-GM

CFU-GM (Colony Forming Unit–Granulocyte–Macrophage), also known as granulocyte–macrophage progenitor (GMP), is a colony forming unit. It is derived from CFU-GEMM. It is the precursor for monoblasts and myeloblasts. Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).

Granulocytes

There is some controversy over which granulocytes derive from CFU-GM.

• There is little disagreement that neutrophils come from CFU-GM.
• Some sources state that basophils also derive from CFU-GM, but that eosinophils come from "CFU-Eos".
• Other sources state that basophils do not derive from CFU-GM, but from a distinct CFU, titled "CFU-Baso".

See also

• Hematopoietic stem cell § Nomenclature of hematopoietic colonies and lineages

Notes

References

External links